Vital Engineering:  A program of UPMC
Bios
Bibliography
Vital Engineering
Bibliography
Vital Engineering's team of bioengineers bring more than 40 years of combined clinical experience to the mechanical circulatory device industry. Outlined below is a selected bibliography categorized by specialty on their recognized work in the field.

Selected Publications

Total Artificial Heart

  1. Griffith BP, Hardesty RL, Kormos RL, Trento A, Borovetz HS and Bahnson HT: Temporary use of the Jarvik-7 total artificial heart prior to transplantation. New Eng J Med 1987;316:130-4.
  2. Griffith BP, Kormos RL, Dummer JS and Hardesty RL: The artificial heart: Infection-related morbidity and its effect on transplantation. Ann Thorac Surg 1988;45(4):409-15.
  3. Borovetz HS, Kormos RL, Hung TC, Griffith BP: Clinical utilization of the artificial heart. In: Critical Reviews of Biomedical Engineering, CRC Press Inc 17(2):179, 1989.
  4. Copeland JC, Arabia FA, Banch ME, Sethi GK, Foy B, Long J, Kormos RL, Smith RG: The CardioWest Total Artificial Heart Bridge to Transplantation 1993 to 1996 National Trial. Ann Thor Surg 1998;66(5):1662-6.

Ventricular Assist Devices

  1. Kormos RL and Griffith BP: Ventricular assist devices. In: Textbook of Critical Care (2nd edition), Shoemaker WJ, Ayres S, Grenvik A, Holbrook P, and Thompson WL (eds). Philadelphia: W.B. Saunders Publishing Co, Chapter 143, 1243-8, 1988.
  2. Kormos RL, Borovetz HS, Gasior T, Antaki JF, Armitage JM, Pristas JM, Hardesty RL, Griffith BP: Experience with univentricular support in mortally ill cardiac transplant candidates. Ann Thor Surg 1990;49(2):261-71.
  3. Woodard J., Shaffer F., Ness R., Schaub R., Lund L., Borovetz H., Portner P.: Optimal Management of a Ventricular Assist System: Contribution of Flow Visualization Studies. Transactions of the American Society for Artificial Internal Organs 38(3):M216-9, 1992.
  4. Wagner WR, Johnson PC, Kormos RL, and Griffith BP: Evaluation of bioprosthetic valve associated thrombosis in ventricular assist device patients. Circulation 1993;88(5)Part1;2023-9.
  5. Pristas JM, Winowich S, Nastala CJ, Gifford, J, Conner EA, Borovetz HS, Griffith BP, Portner PM, Kormos RL: Protocol for releasing Novacor left ventricular assist system patients out-of-hospital. ASAIO Journal 1995:41(3);M539-43.
  6. Griffith BP, Kormos RL, Nastala C, Winowich S, Pristas J: The Results of Extended Bridge to Transplantation: Window into the future of permanent ventricular assist devices. Ann Thorac Surg Circ Suppl 1996:61(1):396-8.
  7. Farrar DJ, Hill JD, Pennington DG, McBride LW, Holman WL, Kormos RL, Esmore D, Gray, Jr. LA, Seifert PE, Schoettle GP, Moore CH, Hendry PJ, Bhayana JN. Preoperative and postoperative comparisons of patients with uni-and bi-ventricular Thoratec VAD support as a bridge to cardiac transplantation. J Thorac Cardiovasc Surg 1997;113(1):202-9.
  8. Mandarino WA, Winowich S, Gorcsan J, Gasior TA, Pham SM, Griffith BP, Kormos RL. Right ventricular performance and left ventricular assist device filling. Annals Thor Surg 1997;63(4):1044-9.
  9. Dew MA, Kormos RL, Winowich S, Nastala CJ, Borovetz HS, Roth LH, Sanchez J, Griffith BP: Quality of life outcomes in left ventricular assist system inpatients and outpatients. ASAIO Journal 1999;45(3):218-25.
  10. Wagner WR, Schaub RD, Sorensen EN, Snyder TA, Wilhelm CR, Winowich S, Borovetz HS, Kormos RL. Blood biocompatilbility analysis in the setting of ventricular assist devices. J Biomat Sci, Polymer Ed, 2000;11:1239-59.

Mechanical Circulatory Support - General

  1. Pristas JM, Borovetz HS, Kormos RL and Griffith BP: Biomedical engineering management of Novacor Left Ventricular Assist System (LVAS) patients. Perfusion 1990;5:181-91.
  2. Kormos RL, Borovetz HS, Armitage JM, Hardesty RL, Marrone GC, and Griffith BP: Evolving experience with mechanical circulatory support. Ann Surg 1991;214(4):471-7.
  3. Kormos RL, Murali S, Dew MA, Armitage JM, Hardesty RL, Borovetz HS, and Griffith BP: Chronic mechanical circulatory support: Rehabilitation, low morbidity and superior survival after heart transplant. Annals of Thoracic Surgery, 1994;57:51-8.
  4. Winowich S, Nastala CJ, Pristas JM, Griffith BP, Kormos RL: Discharging patients who are undergoing mechanical circulatory support. Ann Thorac Surg 1996:61(1);478-9.
  5. Pantalos GM, Altieri F, Berson A, Borovetz H, Butler K, Byrd G, Ciarkowski AA, Dunn R, Frazier OH, Griffith BP, Hoeppner, Jassawalla JS, Kormos RL, Kung RTV, Lemperle B, Lewis JP, Pennington DG, Poirier VL, Portner PM, Rosenberg G, Shanker R, Watson JT: Long-term mechanical circulatory support system reliability recommendation (ASAIO and STS long-term mechanical circulatory support system reliability recommendation). Ann Thorac Society 1998;66:1852-9.
  6. Boujoukos AJ, Winowich S. Monitoring of Cardiac Assist Devices, Principles and Practice of Intensive Care Monitoring, Ed: Tobin MJ. New York: McGraw Hill, Inc. 1998, 54:963-76.
  7. Schaub R., Kameneva M., Borovetz H., Wagner W.: Assessing acute platelet adhesion on opaque metallic and polymeric Biomaterials with fiber optic microscopy. J Biomed Mat Res 2000;49(4):460-8.

Axial Flow Pump

  1. Litwak P, Butler KC, Thomas DC, Taylor LP, Macha M, Yamazaki k, Konishi H, Kormos RL, Griffith BP, Borovetz HS: Development and initial testing of a pediatric centrifugal blood pump. Ann Thorac Surg 1996;61(1):448-51.
  2. Butler K, Thomas DT, Antaki J, Borovetz H, Griffith B, Kameneva M, Kormos R, Litwak P. Development of the Nimbus/Pittsburgh Axial Flow Left Ventricular Assist System. Artif Organs 1997;21(7):602-10.
  3. Butler KC, Dow JJ, Litwak P, Kormos RL, Borovetz HS: Development of the Nimbus/University of Pittsburgh Innovative Ventricular Assist System. Ann Thorac Surg 1999;68(2):790-4.

Recent Abstracts/Presentations

  1. Severyn DA, Winowich S, Schaub RD, Kormos RL. Five year experience with an interdisciplinary intra-aortic balloon pump transport team, ASAIO Abs 2000; 29:188.
  2. Winowich S, Schaub RD, Severyn DA, Borovetz HS, Stanford EA, Carozza LJ, Griffith BP, McCurry KR, Kormos RL. Utilization of "short term" (ST) cardiac assist technology as a bridge to "long term" (LT) systems in the acutely ill, ASAIO Abs 2000; 29:163.
  3. Schaub RD, Patzer JF, Severyn DA, Winowich S, Kormos RL, Borovetz HS. Bioengineering considerations in the clinical trial of a bioartificial liver, Ann Biomed Eng 2000;28:S5.
  4. Severyn DA, Gorcsan J, Schaub RD, Winowich S, Stanford EA, Carozza LJ, Borovetz HS, Kormos RL. Searching for candidates to be weaned off of ventricular assist devices: A team approach, Ann Biomed Eng 2000;28:S5.
  5. Winowich S, Bedi M, Schaub RD, Severyn DA, Sorensen EN, Borovetz HS, Griffith BP, Weiss R, Kormos RL. Rate of readmission due to arrhythmias in outpatients with ventricular assist devices, ASAIO 2001;47(2):132.
  6. Severyn DA, Sorensen EN, Winowich S, Schaub R, Kormos RL. Clinical variation in ventricular assist device generated arterial pressure waveforms, ASAIO 2001;47(2):167.
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